Clinical Practice Resources - Lasers



1.         Strong MS, Jako GJ. Laser surgery in the larynx. Early clinical experience with continuous CO2 laser. Ann Otol Rhinol Laryngol 1972; 81:791-798.

            First report of laser use in the larynx.


2.         Anderson RR, Parrish JA. Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation. Science 1983; 220:524-527.

            Seminal article detailing the physics behind today’s angiolytic lasers.


3.         Ossoff RH, Sisson GA, Duncavage JA, Moselle HI, Andrews PE, McMillan WG. Endoscopic laser arytenoidectomy for the treatment of bilateral vocal cord paralysis. Laryngoscope 1984; 94:1293-1297.

Excellent historical review of surgeries to treat airway obstruction in bilateral vocal fold paralysis and first well-illustrated description of endoscopic arytenoidectomy via CO2 laser ablation.


4.         Hirano M, Hirade Y. CO2 laser for treating glottic carcinoma. Acta Otolaryngol Suppl 1988; 458:154-157.

Early use of CO2 laser for varying depths of resection to narrow glottic cancer margins.


5.         Steiner W. Results of curative laser microsurgery of laryngeal carcinomas. Am J Otolaryngol 1993; 14:116-121.

            Landmark paper on transoral (CO2) laser microsurgery for laryngeal cancer.


6.         Cholewa D, Waldschmidt J. Laser treatment of hemangiomas of the larynx and trachea. Lasers Surg Med 1998; 23:221-232.

Excellent review of large series of laryngotracheal hemangiomas treated with Nd:YAG laser.


7.         Benninger MS. Microdissection or microspot CO2 laser for limited vocal fold benign lesions: a prospective randomized trial. Laryngoscope 2000; 110:1-17.

Randomized controlled trial; also Triologic thesis with excellent discussion of laser physics and their use in the larynx.


8.         Zeitels SM, Franco RA, Jr., Dailey SH, Burns JA, Hillman RE, Anderson RR. Office-based treatment of glottal dysplasia and papillomatosis with the 585-nm pulsed dye laser and local anesthesia. Ann Otol Rhinol Laryngol 2004; 113:265-276.

            First report in the literature of unsedated, office-based photoangiolytic laser treatment in the larynx.


9.         Zeitels SM, Burns JA, Akst LM, Hillman RE, Broadhurst MS, Anderson RR. Office-based and microlaryngeal applications of a fiber-based thulium laser. Ann Otol Rhinol Laryngol 2006; 115:891-896.

First report on use of thulium laser for unsedated, office-based as well as operative laryngeal procedures; compares thulium to CO2 laser.


10.       Zeitels SM, Burns JA, Lopez-Guerra G, Anderson RR, Hillman RE. Photoangiolytic laser treatment of early glottic cancer: a new management strategy. Ann Otol Rhinol Laryngol Suppl 2008; 199:3-24.

First report of KTP laser for treatment of early glottic cancer.


11.       Peretti G, Piazza C, Cocco Det al. Transoral CO(2) laser treatment for T(is)-T(3) glottic cancer: the University of Brescia experience on 595 patients. Head Neck 2010; 32:977-983.

            Large series of glottic cancer patients treated with CO2 laser.


12.       Day AT, Rivera E, Farlow JL, Gourin CG, Nussenbaum B. Surgical Fires in Otolaryngology: A Systematic and Narrative Review. Otolaryngol Head Neck Surg 2018; 158:598-616.

Systematic review of surgical fires in otolaryngology, a substantial portion of which involved endoscopic laryngotracheal procedures with lasers.